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Iran retaliated with strikes across the Middle East. Travel across the region is disrupted.

The U.S.-Israeli attack raises the risk of major oil supply disruption. Iran is the fourth-largest OPEC producer and sits on the critical Strait of Hormuz.

In a scathing review, the top US medical journal's editorial board warned that the "destruction that Kennedy has wrought in 1 in office might take generations to repair."

An Israeli spokesman named three senior Iranian officials killed in a day of strikes but made no mention of the fate of Iran’s supreme leader. President Trump called on Iranians to overthrow their government.

A major hub in Dubai has suspended operations following U.S.-Israeli strikes on Iran. The sweeping closures are stranding passengers.

The strike on an elementary school in the southern Iran town of Minab was one of two attacks that appear to have hit schools during U.S. and Israeli strikes on Iran on Saturday.

Governments around the world urged restraint after the United States and Israel launched a major assault, and Iran vowed retaliation.

The missile barrages highlight a shortage of bomb shelters in a country that has been preparing for war with Iran for decades.

At least one gathering of senior officials and military leaders was hit, but it was not immediately clear whether the effort to kill them had succeeded.

See images from the Middle East after the United States and Israel on Saturday launched a major attack against Tehran.

Maps show where U.S. and Israel have struck Iran, and where Iran has retaliated.

The U.S. military hit Iran’s missile sites, air defense systems, and command and control centers for the Iranian Revolutionary Guard Corps. Iran’s main intelligence agency was targeted, an official said.

Israeli prime minister addresses media after US and Israel launch major combat operation against Iran; at least 201 people killed in Iran, media reports sayFull report: US and Israel attack IranAnalysis: Trump’s attack has no mandateA visual guide to the US-Israeli strikes on Iran – and Tehran’s responseBlasts have been heard in several cities, including the capital, Tehran, and Isfahan in central Iran.Reuters reports there are long queues at petrol stations in the capital, as many people try to leave. An unnamed Iranian official who spoke to the news agency said several ministries in southern Tehran had been targeted. Continue reading...

Regime could try to retain control of streets as US and Israel have expressed no intention of mounting ground invasionVenezula’s Nicholás Maduro was captured. But Donald Trump and Benjamin Netanyahu have chosen a different strategy for Iran: to target and aim to kill the country’s supreme leader, Ali Khamenei, , and as many other senior regime figures as possible.Though Iranian military sites and its air defence systems were also targeted by coordinated US and Israeli bombing, beginning in the morning, the most significant attack was on Khamenei’s compound in Tehran. Continue reading...

Makerfield MP has been under pressure over thinktank’s commissioning of PR firm to investigate reportersThe Labour minister Josh Simons has resigned from the government after the Guardian revealed that he falsely linked reporters to a “pro-Kremlin” network in emails to GCHQ despite having claimed to be “surprised” and “furious” about a PR firm’s investigation into their journalism.Simons, who had been a Cabinet Office minister, previously ran the thinktank Labour Together. He quit on Saturday, saying his position in office had become “a distraction from this government’s important work.” Continue reading...

Tehran carries out extensive retaliatory strikes on Israel and US air bases as region is plunged into fresh conflictUS-Israeli attack on Iran – live updatesUS and Israel strikes on Iran – what we know so farIsrael and the US have launched a war on Iran, unleashing waves of air attacks across the country in an attempt to bring about regime change and plunging the region into a conflict that could last weeks or months.The sudden offensive triggered Iranian retaliatory strikes throughout the day across a swathe of the Middle East, with explosions reported in Israel, Bahrain, Syria, Iraq, the United Arab Emirates, Kuwait and Saudi Arabia. Continue reading...

Joint operation prompts Tehran to retaliate with missile attacks on bases across Middle EastFull reportUS-Israeli attack on Iran – live updatesA visual guide to US-Israeli strikes on Iran – and Tehran’s responseThe US and Israel have launched a joint military operation against Iran, prompting Tehran to fire retaliatory strikes against Israeli and US bases across the Middle East.Explosions rocked the Iranian capital, Tehran, with satellite imagery showing extensive damage at the secure compound of the country’s supreme leader, Ayatollah Ali Khamenei.In a televised address, the Israeli prime minister, Benjamin Netanyahu, indicated that the strikes had killed Khamenei. Iran’s leader has not been heard from since the strikes began. “There are many signs that [Khamenei] is no longer alive,” Netanyahu said on Saturday evening. Netanyahu said that Israeli strikes had also killed “several leaders” involved in the Iranian nuclear programme and that strikes against sites linked to the programme would continue in the coming days. The remarks, which stopped short of confirming Khamenei’s death, were the strongest official indication yet that the missing leader is dead.Dozens of students were reportedly killed in a strike on a primary school in the south-east. Iranian media is reporting at least 201 people have been killed in total and 747 injured.Abbas Araghchi, the Iranian foreign minister who has been leading the nuclear talks for the Iranian delegation, promised that Iran’s army would “teach aggressors the lesson they deserve”.Further explosions were reported in Gulf countries, including the United Arab Emirates, Bahrain, Qatar and Kuwait, all of which host US military bases. One person was killed by shrapnel from an Iranian missile in Abu Dhabi, UAE officials said.The US president, Donald Trump, described the US military campaign as “massive and ongoing” as he called on the people of Iran to “take over your government”. In a speech posted on Truth Social, he said the US would “raze their [Iran’s] missile industry to the ground” and claimed Tehran had refused to reach a deal with the US that would have averted war.Netanyahu said the US-Israeli attack could “create the conditions for the brave Iranian people to take their destiny into their own hands”. Continue reading...

War launched by US and Israel on Iran has quickly escalated prompting anxiety and concern in whole regionFull reportUS-Israeli attack on Iran – live updatesIran struck the world-famous Fairmont hotel in Dubai, setting the hotel alight, as the war launched by the US and Israel on Iran quickly spread to the rest of the Middle East on Saturday.Residents watched in shock as an Iranian missile hit the five-star hotel in Dubai’s luxurious Palm Jumeirah area. Social media videos showed fires breaking out near the entrance of the hotel, which led to four people being injured. Continue reading...

HBO is owned by Warner Bros. Discovery, which is currently in the midst of a high-profile takeover

Now the gloves are off, and each side will be trying to land a knockout blow

Iran’s Red Crescent says at least 201 people were killed in the US-Israeli strikes on Saturday, according to Iranian media

Several members of Trump’s cabinet have previously spoken out against foreign interventions

The US and Israel launched strikes against Iranian targets overnight, prompting retaliation by Tehran

The U.S has released footage showing the moment it launched strikes on Iran from an aircraft carrier.

The former Fox News host made the remarks to ABC White House correspondent Jonathan Karl

U.S. and Israel launch a major attack on Iran. Trump urges Iranians to ‘take over’  Toronto StarExclusive: Trump floats "off ramps" after attacking Iran  AxiosIsrael's Netanyahu says 'signs' point to Khamenei being dead  DW.comLive updates: Israeli officials say Iran’s supreme leader is dead, but US and Iran haven’t confirmed  AP NewsWhat to know about the new US-Israel attacks on Iran  Toronto Star

Liverpool boosted their Champions League hopes with a 5-2 win against West Ham, helped by three goals from set-pieces in the first half.

BA, Virgin Atlantic and Wizz Air are among major airlines to overhaul their schedules in light of the attacks.

Newcastle are languishing in 12th place in the Premier League for a reason - they have conceded 23 goals since they last kept a clean sheet in any competition.

Simons faced claims the think tank he used to run commissioned a report which looked into the background of journalists.

Iran has retaliated with a missile barrage towards Israel, while explosions have been heard in Qatar, Bahrain, Kuwait and the UAE.

Stars including Olivia Dean, Lola Young and Rosalía turned out for the Brit Awards in Manchester.

Iran's strike on US Navy base in Bahrain will worry Washington and its allies in the region.

Sir Keir Starmer says protections for British bases and personnel have been stepped up to their highest level.

This is a breaking news story.

Israeli Prime Minister Benjamin Netanyahu claims Iranian Supreme Leader Ali Khamenei may be "no longer alive."

Iranians receive mixed messages amid ongoing attacks, internet shutdown and limited mobile connectivity.

“This is the second time in less than a year that diplomacy was betrayed by the Americans.”

Donald Trump promised voters that he would end wars, not start them.

U.S. military interventions have often gone poorly for the countries in question. But there is much the world, and Iranians, can do.

At least one gathering of senior officials and military leaders was hit, but it was not immediately clear whether the effort to kill them had succeeded.

Maps show where U.S. and Israel have struck Iran, and where Iran has retaliated.